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Static lung volumes and airway resistance reference values in healthy adults.
MedLine Citation:
PMID:  23279785     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Background and objective:  The assessment of static lung volumes and airway resistance is a frequently performed diagnostic procedure and considered as an important tool in medical surveillance to detect pulmonary diseases. The objectives of the study are to establish reference equations for body plethysmographic parameters in a representative adult population across a wide age range and to compare the normative values from this sample with previous ones. Methods:  Body plethysmography was applied in 1809 participants (885 males) of a cross-sectional, population-based survey (Study of Health in Pomerania). Individuals with cardiopulmonary disorders and/or a pack-year smoking history >10 years and participants with a body mass index >30 kg/m(2) were excluded. In total, 686 healthy individuals (275 males) aged 25-85 years were assessed. Results:  Prediction equations for both genders were established by quantile regression analysis taking into account the influence of age, height and weight. Conclusions:  The study provides a novel set of prediction equations for static lung volumes and airway resistance obtained using body plethysmography. Compared with our findings, existing equations underestimated some normal values. The results emphasize the need for up-to-date reference equations.
Authors:
Beate Koch; Nele Friedrich; Henry Völzke; Rudolf A Jörres; Stefan B Felix; Ralf Ewert; Christoph Schäper; Sven Gläser
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Respirology (Carlton, Vic.)     Volume:  18     ISSN:  1440-1843     ISO Abbreviation:  Respirology     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9616368     Medline TA:  Respirology     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  170-8     Citation Subset:  IM    
Copyright Information:
© 2012 The Authors. Respirology © 2012 Asian Pacific Society of Respirology.
Affiliation:
Department of Internal Medicine B, Cardiology, Pneumology, Infectious Diseases, Intensive Care Medicine Institute of Clinical Chemistry and Laboratory Medicine Institute for Community Medicine, SHIP/Clinical-Epidemiological Research, Ernst-Moritz-Arndt University, Greifswald Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-University, Munich, Germany.
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