Document Detail


Static footprint analysis: a time-saving functional evaluation of nerve repair in rats.
MedLine Citation:
PMID:  15841798     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Walking track analysis is a widely accepted technique for functional evaluation after sciatic nerve repair in rats, but it is labour-intensive. In 2000, Bervar described a time-saving digitised static footprint analysis. In that study there were good correlations between the traditional sciatic function index (SFI) and the newly-developed static sciatic index (SSI) and static toe spread factor (TSF), respectively. Despite promising results, static footprint analysis is still not widely used. The present study was designed to validate it. After transection of the sciatic nerve, end-to-end repair was assessed using video recorded dynamic and static footprints in 45 Wistar rats. We found an even better correlation between the SFI and both the SSI and the static TSF. In conclusion, static footprint analysis is a time-saving and easy technique for accurate functional assessment of peripheral nerve regeneration in rats.
Authors:
Xander Smit; Johan W van Neck; Menno J Ebeli; Steven E R Hovius
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Validation Studies    
Journal Detail:
Title:  Scandinavian journal of plastic and reconstructive surgery and hand surgery / Nordisk plastikkirurgisk forening [and] Nordisk klubb for handkirurgi     Volume:  38     ISSN:  0284-4311     ISO Abbreviation:  Scand J Plast Reconstr Surg Hand Surg     Publication Date:  2004  
Date Detail:
Created Date:  2005-04-21     Completed Date:  2005-05-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8707869     Medline TA:  Scand J Plast Reconstr Surg Hand Surg     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  321-5     Citation Subset:  IM    
Affiliation:
Department of Plastic and Reconstructive Surgery, Erasmus MC - University Medical Center Rotterdam, The Netherlands. x.smit@erasmusmc.nl
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MeSH Terms
Descriptor/Qualifier:
Animals
Female
Nerve Regeneration*
Rats
Rats, Wistar
Sciatic Nerve / injuries,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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