| Static and dynamic (18) fdg-pet in normal hispaniolan Amazon parrots (amazona ventralis). | |
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MedLine Citation:
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PMID: 21554485 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Positron emission tomography (PET) is often used to stage and monitor human cancer and has recently been used in a similar fashion in veterinary medicine. The most commonly used radiopharmaceutical is 2-Deoxy-2-[(18) F]-Fluoro-d-glucose ((18) F-FDG), which is concentrated and trapped within cells that use glucose as their energy substrate. We characterized the normal distribution of (18) F-FDG in 10 healthy Hispaniolan Amazon parrots (Amazona ventralis) by performing whole body PET scans at steady state, 60 min after injection. Significant variability was found in the intestinal activity. Avian species are known to reflux fluid and electrolytes from their cloaca into their colon. To evaluate reflux as the cause of variability in intestinal distribution of (18) F-FDG, dynamic PET scans were performed on the coelomic cavity of six Hispaniolan Amazon parrots from time 0 to 60 min postinjection of radiotracer. Reflux of radioactive material from the cloaca into the colon occurred in all birds to varying degrees and occurred before 60 min. To evaluate the intestinal tract of clinical avian patients, dynamic scans must be performed starting immediately after injection so that increased radioactivity due to metabolism or hypermetabolic lesions such as cancer can be differentiated from increased radioactivity due to reflux of fluid from the cloaca. |
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Authors:
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Marcy J Souza; Jonathan S Wall; Alan Stuckey; Gregory B Daniel |
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Publication Detail:
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Type: Journal Article Date: 2010-12-28 |
Journal Detail:
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Title: Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association Volume: 52 ISSN: 1058-8183 ISO Abbreviation: Vet Radiol Ultrasound Publication Date: 2011 May-Jun |
Date Detail:
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Created Date: 2011-05-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9209635 Medline TA: Vet Radiol Ultrasound Country: United States |
Other Details:
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Languages: eng Pagination: 340-4 Citation Subset: IM |
Copyright Information:
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© 2010 Veterinary Radiology & Ultrasound. |
Affiliation:
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Department of Comparative Medicine, University of Tennessee, College of Veterinary Medicine, Knoxville, TN 37996 Departments of Medicine and Radiology, University of Tennessee Graduate School of Medicine, Knoxville, TN 37920 Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, VA 24061. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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