Document Detail

Statement on intra-uterine insemination.
MedLine Citation:
PMID:  8719864     Owner:  NLM     Status:  MEDLINE    
Treatment of couple infertility due to male subfertility by means of intra-uterine insemination (IUI) gives better results, in terms of per cycle and total cumulative pregnancy rate, if sperm preparation is performed using a discontinuous Percoll gradient than if centrifugation-resuspension is used. Also, the minimal semen requirements for successful IUI are lower with the former technique. Optimal epididymal function, with total alpha-glucosidase activity in seminal plasma > 83 IU/mL or Schorr stain result > 60%, is associated with a high probability of success of IUI [odds ratio (OR) = 11.1 and 9.4 respectively; p < 0.01]. If semen contains > 2.3 million white blood cells per mL or more than 13 million spermatozoa/mL with grade a motility the success rate is decreased (OR = 0.25 and 0.30 respectively; p < 0.05 and p < 0.01). It is concluded that IUI is a highly successful treatment in specific cases of male subfertility, provided that the correct technique of sperm preparation is used.
F Comhaire; H Depypere; S Millingos
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International journal of andrology     Volume:  18 Suppl 2     ISSN:  0105-6263     ISO Abbreviation:  Int. J. Androl.     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-12-03     Completed Date:  1996-12-03     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8000141     Medline TA:  Int J Androl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  76-7     Citation Subset:  IM    
Andrology Laboratory, University Hospital, Department of Endocrinology, Ghent, Belgium.
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MeSH Terms
Infertility, Male / therapy*
Insemination, Artificial / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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