| Statement on intra-uterine insemination. | |
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MedLine Citation:
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PMID: 8719864 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Treatment of couple infertility due to male subfertility by means of intra-uterine insemination (IUI) gives better results, in terms of per cycle and total cumulative pregnancy rate, if sperm preparation is performed using a discontinuous Percoll gradient than if centrifugation-resuspension is used. Also, the minimal semen requirements for successful IUI are lower with the former technique. Optimal epididymal function, with total alpha-glucosidase activity in seminal plasma > 83 IU/mL or Schorr stain result > 60%, is associated with a high probability of success of IUI [odds ratio (OR) = 11.1 and 9.4 respectively; p < 0.01]. If semen contains > 2.3 million white blood cells per mL or more than 13 million spermatozoa/mL with grade a motility the success rate is decreased (OR = 0.25 and 0.30 respectively; p < 0.05 and p < 0.01). It is concluded that IUI is a highly successful treatment in specific cases of male subfertility, provided that the correct technique of sperm preparation is used. |
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Authors:
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F Comhaire; H Depypere; S Millingos |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: International journal of andrology Volume: 18 Suppl 2 ISSN: 0105-6263 ISO Abbreviation: Int. J. Androl. Publication Date: 1995 Dec |
Date Detail:
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Created Date: 1996-12-03 Completed Date: 1996-12-03 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 8000141 Medline TA: Int J Androl Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 76-7 Citation Subset: IM |
Affiliation:
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Andrology Laboratory, University Hospital, Department of Endocrinology, Ghent, Belgium. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Humans Infertility, Male / therapy* Insemination, Artificial / methods* Male |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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