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State of research: environmental pathways and food chain transfer.
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MedLine Citation:
PMID:  6428875     Owner:  NLM     Status:  MEDLINE    
Data on the chemistry of biologically active components of petroleum, synthetic fuel oils, certain metal elements and pesticides provide valuable generic information needed for predicting the long-term fate of buried waste constituents and their likelihood of entering food chains. Components of such complex mixtures partition between solid and solution phases, influencing their mobility, volatility and susceptibility to microbial transformation. Estimating health hazards from indirect exposures to organic chemicals involves an ecosystem's approach to understanding the unique behavior of complex mixtures. Metabolism by microbial organisms fundamentally alters these complex mixtures as they move through food chains. Pathway modeling of organic chemicals must consider the nature and magnitude of food chain transfers to predict biological risk where metabolites may become more toxic than the parent compound. To obtain predictions, major areas are identified where data acquisition is essential to extend our radiological modeling experience to the field of organic chemical contamination.
B E Vaughan
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Environmental health perspectives     Volume:  54     ISSN:  0091-6765     ISO Abbreviation:  Environ. Health Perspect.     Publication Date:  1984 Mar 
Date Detail:
Created Date:  1984-08-08     Completed Date:  1984-08-08     Revised Date:  2010-09-10    
Medline Journal Info:
Nlm Unique ID:  0330411     Medline TA:  Environ Health Perspect     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  353-71     Citation Subset:  IM    
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MeSH Terms
Air Pollutants / metabolism
Benzofurans / metabolism
Environmental Pollutants / metabolism*
Food Contamination*
Models, Biological
Plants / metabolism
Polychlorinated Biphenyls / metabolism
Polycyclic Compounds / metabolism
Soil Pollutants / metabolism
Water Pollutants, Chemical / metabolism
Reg. No./Substance:
0/Air Pollutants; 0/Benzofurans; 0/Environmental Pollutants; 0/Polychlorinated Biphenyls; 0/Polycyclic Compounds; 0/Soil Pollutants; 0/Water Pollutants, Chemical; 0/chlorinated dibenzofurans

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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Journal Information
Journal ID (nlm-ta): Environ Health Perspect
ISSN: 0091-6765
Article Information
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Print publication date: Month: 3 Year: 1984
Volume: 54First Page: 353 Last Page: 371
ID: 1568158
PubMed Id: 6428875

State of research: environmental pathways and food chain transfer.
B E Vaughan

Article Categories:
  • Research Article

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