Document Detail

State of the art and new horizons in the diagnosis and management of egg allergy.
MedLine Citation:
PMID:  19912153     Owner:  NLM     Status:  MEDLINE    
Egg allergy is one of the most frequent food allergies in children below the age of three. Common symptoms of egg allergy involve frequently the skin as well as the gut and in more severe cases result in anaphylaxis. Non-IgE-mediated symptoms such as in eosinophilic diseases of the gut or egg-induced enterocolitis might also be observed. Sensitization to egg white proteins can be found in young children in absence of clinical symptoms. The diagnosis of egg allergy is based on the history, IgE tests as well as standardized food challenges. Ovomucoid is the major allergen of egg, and recent advances in technology have improved the diagnosis and follow-up of patients with egg allergy by using single allergens or allergens with modified allergenic properties. Today, the management of egg allergy is strict avoidance. However, oral tolerance induction protocols, in particular with egg proteins with reduced allergenic properties, are promising tools for inducing an increased level of tolerance in specific patients.
A H Benhamou; J-C Caubet; P A Eigenmann; A Nowak-Wegrzyn; C P Marcos; M Reche; A Urisu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-11-12
Journal Detail:
Title:  Allergy     Volume:  65     ISSN:  1398-9995     ISO Abbreviation:  Allergy     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-27     Completed Date:  2010-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7804028     Medline TA:  Allergy     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  283-9     Citation Subset:  IM    
Children's Hospital, Geneva University Hospitals, Geneva, Switzerland.
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MeSH Terms
Allergy and Immunology / trends*
Egg Hypersensitivity / diagnosis*,  therapy*

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