Document Detail


The state of disparities in opportunistic infection prophylaxis for blacks with HIV/AIDS.
MedLine Citation:
PMID:  23047780     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The purpose of this review is to identify and analyze published studies that have evaluated disparities for opportunistic infection (OI) prophylaxis between blacks and whites with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) in the United States.
METHODS: The authors conducted a web-based search of MEDLINE (1950-2009) to identify original research articles evaluating the use of OI prophylaxis between blacks and whites with HIV/AIDS. The search was conducted utilizing the following MeSH headings and search terms alone and in combination: HIV, AIDS, Black, race, ethnicity, disparities, differences, access, opportunistic infection, and prophylaxis. The search was then expanded to include any relevant articles from the referenced citations of the articles that were retrieved from the initial search strategy. Of the 29 articles retrieved from the literature search, 19 articles were excluded.
RESULTS: Ten publications met inclusion criteria, collectively published between 1991 and 2005. The collective time periods of these studies spanned from 1987 to 2001. Four studies identified a race-based disparity in that blacks were less likely than whites to use OI prophylaxis, whereas 5 studies failed to identify such a relationship between race and OI prophylaxis. One study identified disparities for Mycobacterium avium complex prophylaxis, but not for Pneumocystis jiroveci pneumonia prophylaxis.
CONCLUSIONS: The evidence regarding race-based disparities in OI prophylaxis is inconclusive. Additional research is warranted to explore potential race-based disparities in OI prophylaxis.
Authors:
Christine U Oramasionwu; Jim M Koeller; Kenneth A Lawson; Carolyn M Brown; Gene D Morse; Christopher R Frei
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Medical care     Volume:  50     ISSN:  1537-1948     ISO Abbreviation:  Med Care     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-10     Completed Date:  2013-01-07     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  0230027     Medline TA:  Med Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  920-7     Citation Subset:  IM    
Affiliation:
UNC Eshelman School of Pharmacy, Division of Pharmaceutical Outcomes and Policy, University of North Carolina at Chapel Hill, 2215 Kerr Hall, Chapel Hill, NC 27599-7573, USA. oramsc@unc.edu
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MeSH Terms
Descriptor/Qualifier:
AIDS-Related Opportunistic Infections / ethnology*,  prevention & control*
African Americans / statistics & numerical data*
Antibiotic Prophylaxis / statistics & numerical data*
HIV Infections / ethnology
Healthcare Disparities / ethnology*
Humans
United States / epidemiology
Vaccination / statistics & numerical data*
Grant Support
ID/Acronym/Agency:
D43TW007991-01A2/TW/FIC NIH HHS; L60 MD003770/MD/NIMHD NIH HHS; U01AI068636/AI/NIAID NIH HHS
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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