Document Detail


Starvation-induced true diabetic euglycemic ketoacidosis in severe depression.
MedLine Citation:
PMID:  18975036     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
True euglycemic diabetic ketoacidosis [blood glucose <200 mg/dl (11.1 mmol/l)] is relatively uncommon and in type 1 diabetes can be caused by starvation of any cause in conjunction with an intercurrent illness. We report a case of euglycemic diabetic ketoacidosis precipitated by starvation resulting from severe depression in a patient with type 1 diabetes. He was acidotic with ketonuria, but his blood glucose was only 105 mg/dl (5.8 mmol/l). He was rehydrated, the acidosis was corrected, and his depression was later treated. This case involves the complex interplay among type 1 diabetes, depression, ketoacidosis, and starvation physiology resulting in glucose concentrations in keeping with euglycemic diabetic ketoacidosis. The case also highlights that even in the absence of hyperglycemia, acid/base status should be assessed in an ill patient with diabetes, and in cases of euglycemic diabetic ketoacidosis, the diagnosis of depression should be considered as a cause for suppressed appetite and anorexia.
Authors:
Franklin Joseph; Lydia Anderson; Niru Goenka; Jiten Vora
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-10-31
Journal Detail:
Title:  Journal of general internal medicine     Volume:  24     ISSN:  1525-1497     ISO Abbreviation:  J Gen Intern Med     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-24     Completed Date:  2009-10-07     Revised Date:  2013-06-05    
Medline Journal Info:
Nlm Unique ID:  8605834     Medline TA:  J Gen Intern Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  129-31     Citation Subset:  IM    
Affiliation:
Diabetes Centre, Countess of Chester NHS Foundation Trust, Chester, UK.
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MeSH Terms
Descriptor/Qualifier:
Adult
Depressive Disorder / complications*,  diagnosis,  psychology
Diabetes Mellitus, Type 1 / complications*,  diagnosis,  psychology
Diabetic Ketoacidosis / diagnosis,  etiology*,  psychology
Humans
Male
Starvation / complications*,  diagnosis,  psychology
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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