Document Detail


Starvation-induced pathobiology in the gut of carp (Cyprinus carpio L.).
MedLine Citation:
PMID:  11314585     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to assess the effects of starvation on intestinal intraepithelial lymphocytes (i-IEL) count and histological changes of the carp gut mucosa, one group of fish (n = 10) were fed commercially prepared standard diets and another group of fish (n = 10) were starved for 4 weeks. Carp starved for 4 weeks developed enteropathy, comprising folds atrophy, stratum compactum hyperplasia, significant periodic-acid-Schiff (PAS)-positive (P < 0.00001), but not Alcian blue (ALB)-positive, goblet cell (GC) hyperplasia and a significant decrease (P < 0.00001) in i-IEL numbers. These changes were associated with a dense cellular infiltrate into the lamina propria. Taken together, these data suggest that the pathobiology of starvation-induced i-IELs decrease, matching PAS-positive goblet cell proliferation and inflammatory cells homing to the gut, could be classified as a non-infectious enteropathy induced by starvation.
Authors:
F Bozić; E Srebocan; Z Kozarić
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Berliner und Münchener tierärztliche Wochenschrift     Volume:  114     ISSN:  0005-9366     ISO Abbreviation:  Berl. Munch. Tierarztl. Wochenschr.     Publication Date:    2001 Mar-Apr
Date Detail:
Created Date:  2001-04-20     Completed Date:  2001-06-14     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0003163     Medline TA:  Berl Munch Tierarztl Wochenschr     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  134-8     Citation Subset:  IM    
Affiliation:
Department of Pharmacology & Toxicology, Veterinary Faculty, University of Zagreb, Heinzelova 55, 10000 Zagreb, Croatia. Bozic@mavef.vef.hr
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MeSH Terms
Descriptor/Qualifier:
Animals
Carps*
Fish Diseases / immunology,  pathology*
Intestines / immunology,  pathology*
Lymphocyte Count / veterinary
Starvation / immunology,  pathology,  veterinary*

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