Document Detail


Staphylococcus aureus nasal carriage and its contributing factors.
MedLine Citation:
PMID:  19824791     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Staphylococcus aureus is a medically important pathogen that is often acquired from hospital settings (nosocomial) as well as from the community (community acquired). Bacteria that reside in anterior nares of hosts serve as reservoirs for both the spread of the pathogen and predispose the host to subsequent infections. Here, we will review the extent and variability of nasal carriage, and the possible causative factors--both from the host and the bacterium. We also discuss the existing molecular typing techniques used for studying variations among strains of S. aureus. Finally, we discuss the possible areas of studies that are open in this field. Given the pathogen's importance in healthcare setting, such areas of study vary vastly, from fundamental research to applied medical care and use of alternative medical regimes for control of S. aureus nasal carriage. Unsurprisingly, our conclusions also underscore the importance of making policy decisions based on local ethnic and socioeconomic population structure.
Authors:
Karthikeyan Sivaraman; Nitya Venkataraman; Alexander M Cole
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Future microbiology     Volume:  4     ISSN:  1746-0921     ISO Abbreviation:  Future Microbiol     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-14     Completed Date:  2010-01-12     Revised Date:  2010-12-30    
Medline Journal Info:
Nlm Unique ID:  101278120     Medline TA:  Future Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  999-1008     Citation Subset:  IM    
Affiliation:
SBG, Center for Microbial & Plant Genetics, Katholieke Universiteit Leuven, Leuven, Belgium. k.sivan@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Bacterial Proteins / genetics,  metabolism
Carrier State* / epidemiology,  microbiology
Host-Pathogen Interactions*
Humans
Nose / microbiology*
Risk Factors
Staphylococcal Infections* / epidemiology,  microbiology
Staphylococcus aureus / classification,  genetics,  isolation & purification*
Grant Support
ID/Acronym/Agency:
R01 AI060753/AI/NIAID NIH HHS; R01 AI060753-01A2/AI/NIAID NIH HHS; R01 AI060753-02/AI/NIAID NIH HHS; R01 AI060753-03/AI/NIAID NIH HHS; R01 AI060753-04/AI/NIAID NIH HHS; R01 AI060753-05/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/Bacterial Proteins

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