| Staphylococcal toxic shock syndrome erythroderma is associated with superantigenicity and hypersensitivity. | |
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MedLine Citation:
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PMID: 19911998 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Staphylococcal toxic shock syndrome (TSS) has rarely been reported without rash and desquamation. This study describes a patient who met all criteria for TSS except erythroderma and desquamation. The associated staphylococcal superantigen was enterotoxin B. We demonstrate that erythroderma depends on preexisting T cell hypersensitivity amplified by superantigenicity. |
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Authors:
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Chandy C John; Micah Niermann; Bazak Sharon; Marnie L Peterson; David M Kranz; Patrick M Schlievert |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 49 ISSN: 1537-6591 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-11-25 Completed Date: 2010-01-27 Revised Date: 2011-04-21 |
Medline Journal Info:
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Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: United States |
Other Details:
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Languages: eng Pagination: 1893-6 Citation Subset: IM |
Affiliation:
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Department of 1Pediatrics, University of Minnesota Medical School, Minneapolis, MN 55455, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Dermatitis, Exfoliative / diagnosis, etiology* Enterotoxins / immunology Female Humans Shock, Septic / diagnosis, etiology* Skin Tests Staphylococcal Infections / diagnosis, etiology* Superantigens / immunology* |
| Grant Support | |
ID/Acronym/Agency:
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R01 AI064611-05/AI/NIAID NIH HHS; R01 AI074283-21/AI/NIAID NIH HHS; R01-AI064611/AI/NIAID NIH HHS; U54 AI057153-065876/AI/NIAID NIH HHS; U54-AI57153/AI/NIAID NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Enterotoxins; 0/Superantigens; 39424-53-8/enterotoxin B, staphylococcal |
| Comments/Corrections | |
Comment In:
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Clin Infect Dis. 2010 May 1;50(9):1326; author reply 1326-7
[PMID:
20367234
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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