Document Detail

Standardized technique of laparoscopic surgery in the rat.
MedLine Citation:
PMID:  9845575     Owner:  NLM     Status:  MEDLINE    
The evolution of advanced laparoscopic techniques requires animal models for instrument development, evaluation of the physiopathological correlation and physician training. Selection of surgical models is primarily based on cost, availability, anatomic and physiologic considerations, and housing and anesthetic methods. The use of large animals is becoming increasingly difficult due to restrictive legislation, public concern, and economic factors. A standardized technique of laparoscopic surgery in the rat has been developed to perform procedures in all abdominal regions including fundoplication, splenectomy, nephrectomy, liver resection, herniorraphy, colotomy, colectomy, and retroperitoneal exploration. The equipment consists of a specially designed small animal operating table, a standard arthroscope and micro-instruments. The rat model gives the opportunity to investigate the physiopathological relations and immune functions of laparoscopic procedures, to develop micro-instruments under realistic conditions of a live organism, and it is an excellent training model especially for pediatric and microsurgery. Besides low costs and easy availability, the rat model requires less logistic and financial efforts.
C N Gutt; V Riemer; C Brier; R Berguer; V Paolucci
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Digestive surgery     Volume:  15     ISSN:  0253-4886     ISO Abbreviation:  Dig Surg     Publication Date:  1998  
Date Detail:
Created Date:  1999-01-06     Completed Date:  1999-01-06     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8501808     Medline TA:  Dig Surg     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  135-9     Citation Subset:  IM    
Department of General Surgery, Johann Wolfgang Goethe University, Frankfurt/Main, Germany.
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MeSH Terms
Colectomy / methods
Disease Models, Animal*
Fundoplication / methods
Hepatectomy / methods
Hernia, Inguinal / surgery
Laparoscopy / methods*
Pneumoperitoneum, Artificial
Rats, Sprague-Dawley
Splenectomy / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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