| Standardized phase angle from bioelectrical impedance analysis as prognostic factor for survival in patients with cancer. | |
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MedLine Citation:
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PMID: 20039074 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE: Phase angle (PA), determined by bioelectrical impedance analysis (BIA), has been considered as a prognostic factor in several clinical conditions. The purpose of this study is to investigate PA, after adjusting for sex and age (standardized phase angle; SPA) as a prognostic factor for survival in cancer patients. METHODS: A prospective study was conducted in 195 patients before the first chemotherapy course. BIA was performed in all patients and SPA was calculated. The Kaplan-Meier method was used to calculate survival. The Cox regression method was used to evaluate the independent prognostic effect of PA after adjustment for other variables. RESULTS: Patients with SPA < -1.65 had a smaller survival rate than those with SPA ≥ -1.65 (p < 0.001). Using Cox regression, the mortality rate was higher in patients with SPA < -1.65 (RR 3.12 CI: 2.03-4.79; p < 0.001). After multivariate analysis, patients with PA < -1.65 still presented a higher mortality rate (RR 2.35 CI: 1.41-3.90; p = 0.001). CONCLUSIONS: The present study demonstrates that PA, used as SPA, is an independent prognostic indicator in this group of cancer patients receiving chemotherapy treatment even after adjustment for other prognostic variables. |
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Authors:
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Silvana Iturriet Paiva; Lúcia R Borges; Denise Halpern-Silveira; M Cecília F Assunção; Aluisio J D Barros; M Cristina Gonzalez |
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Publication Detail:
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Type: Journal Article Date: 2009-12-29 |
Journal Detail:
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Title: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer Volume: 19 ISSN: 1433-7339 ISO Abbreviation: Support Care Cancer Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2011-01-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9302957 Medline TA: Support Care Cancer Country: Germany |
Other Details:
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Languages: eng Pagination: 187-92 Citation Subset: IM |
Affiliation:
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Post-graduate Program, Health and Behaviour, Catholic University of Pelotas, Rua Porto Alegre, 492, 96090-520, Pelotas, RS, Brazil, vanapaiva@yahoo.com.br. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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