Document Detail

Standardized growth toxicity testing (Cu, Zn, Pb, and pentachlorophenol) with Helix aspersa.
MedLine Citation:
PMID:  10805992     Owner:  NLM     Status:  MEDLINE    
Juvenile Helix aspersa (1 month, 1 g) were exposed for 4 weeks to food contaminated with copper, zinc, lead, and pentachlorophenol. At concentrations observed in contaminated soils, two essential metals at low levels (Cu and Zn) had a dose-dependent sublethal action on growth. Copper inhibited growth dose-dependently between 1000 and 2000 microg small middle dotg(-1) (EC(50)=1200 microg small middle dotg(-1)), whereas zinc had a toxic effect from 4000 microg small middle dotg(-1) (EC(50)=5500 microg small middle dotg(-1)) on. Lead, a nonessential metal, had no negative effect on growth, unlike cadmium (EC(50)=140 microg small middle dotg(-1)), as reported previously. Pentachlorophenol inhibited growth at a concentration of 500 microg small middle dotg(-1) from the fourth week and 1000 microg small middle dotg(-1) from the first week on. The results obtained with these key organisms in the food chain (consumers) complement those obtained with other land invertebrates (earthworms, springtails, wood-lice, etc.). The findings of the present study and those of earlier studies indicate that juvenile snails are useful organisms for testing the sublethal toxicity of chemicals acting via the food, i.e., the main route of toxicant uptake in land animals.
A Gomot-De Vaufleury
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Ecotoxicology and environmental safety     Volume:  46     ISSN:  0147-6513     ISO Abbreviation:  Ecotoxicol. Environ. Saf.     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-06-08     Completed Date:  2000-06-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7805381     Medline TA:  Ecotoxicol Environ Saf     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  41-50     Citation Subset:  IM    
Copyright Information:
Copyright 2000 Academic Press.
Laboratoire de Biologie et Ecophysiologie (EA 2277 and EA 2280), Faculté des Sciences et Techniques, Université de Franche-Comté, Place Leclerc, Besançon cedex, 25030, France.
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MeSH Terms
Copper / toxicity*
Helix (Snails) / drug effects*,  growth & development
Lead / toxicity*
Pentachlorophenol / toxicity*
Zinc / toxicity*
Reg. No./Substance:
7439-92-1/Lead; 7440-50-8/Copper; 7440-66-6/Zinc; 87-86-5/Pentachlorophenol

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