Document Detail

Standardization of facilitation of compound muscle action potentials using a modified myometer during magnetic stimulation in healthy volunteers.
MedLine Citation:
PMID:  7511526     Owner:  NLM     Status:  MEDLINE    
In 20 normal subjects motor evoked potentials (MEPs) from first dorsal interosseous (FDI) were obtained following transcranial magnetic stimulation during relaxation and voluntary contraction of 2-20% of maximum. A new method to standardize facilitation of MEP using surface EMG and a modified myometer was used. The MEP amplitudes increased significantly at contraction levels of 2%, 10% and 15% of maximum. The latencies decreased significantly at contraction levels of 2%, 5% and 15%. Coefficients of variation of the amplitude decreased from 6.4% during relaxation to approximately 2% during facilitation. In contrast, coefficients of variation of take-off latencies (T-lat) increased significantly from 1.7% during relaxation to approximately 3% during facilitation. The variability of amplitudes and latencies was mainly due to inter-individual variation. The observations in the present study indicate that the actual contraction level should be precisely defined during transcranial magnetic stimulation.
J F Nielsen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Electroencephalography and clinical neurophysiology     Volume:  93     ISSN:  0013-4694     ISO Abbreviation:  Electroencephalogr Clin Neurophysiol     Publication Date:  1994 Feb 
Date Detail:
Created Date:  1994-05-05     Completed Date:  1994-05-05     Revised Date:  2008-09-09    
Medline Journal Info:
Nlm Unique ID:  0375035     Medline TA:  Electroencephalogr Clin Neurophysiol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  75-9     Citation Subset:  IM    
Department of Neurology, Arhus University Hospital, Denmark.
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MeSH Terms
Action Potentials / physiology*
Magnetics / diagnostic use*
Middle Aged
Muscles / physiology*
Reaction Time / physiology
Reference Standards
Reference Values

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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