Document Detail


Standardisation of 18F by a coincidence method using full solid angle detectors.
MedLine Citation:
PMID:  20106673     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A solution of (18)F was standardised with a 4pibeta-4pigamma coincidence counting system in which the beta detector is a one-inch diameter cylindrical UPS89 plastic scintillator, positioned at the bottom of a well-type 5''x5'' NaI(Tl) gamma-ray detector. Almost full detection efficiency-which was varied downwards electronically-was achieved in the beta-channel. Aliquots of this (18)F solution were also measured using 4pigamma NaI(Tl) integral counting and Monte Carlo calculated efficiencies as well as the CIEMAT-NIST method. Secondary measurements of the same solution were also performed with an IG11 ionisation chamber whose equivalent activity is traceable to the Système International de Référence through the contribution IRA-METAS made to it in 2001; IRA's degree of equivalence was found to be close to the key comparison reference value (KCRV). The (18)F activity predicted by this coincidence system agrees closely with the ionisation chamber measurement and is compatible within one standard deviation of the other primary measurements. This work demonstrates that our new coincidence system can standardise short-lived radionuclides used in nuclear medicine.
Authors:
Youcef Nedjadi; Claude Bailat; Yvan Caffari; François Bochud
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Publication Detail:
Type:  Journal Article     Date:  2010-01-13
Journal Detail:
Title:  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine     Volume:  68     ISSN:  1872-9800     ISO Abbreviation:  Appl Radiat Isot     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-05-24     Completed Date:  2010-08-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9306253     Medline TA:  Appl Radiat Isot     Country:  England    
Other Details:
Languages:  eng     Pagination:  1309-13; discussion 1313     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Institut de Radiophysique Appliquée, Lausanne, Switzerland. youcef.nedjadi@chuv.ch
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MeSH Terms
Descriptor/Qualifier:
Fluorine Radioisotopes / standards*
Methods
Nuclear Medicine / methods
Reference Standards
Scintillation Counting / instrumentation*,  methods
Chemical
Reg. No./Substance:
0/Fluorine Radioisotopes

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