| Staging of renal cell carcinoma. | |
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MedLine Citation:
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PMID: 17318606 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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As in other malignant tumors, prognosis in renal cell carcinoma (RCC) depends on tumor extent and metastasis at the time of primary diagnosis. Staging systems formalize the way in which the extent of RCC is being described and classified. Primary staging of RCC aims at evaluating surgical options. Since surgical excision, which is the mainstay of therapy in non-metastatic RCC, and, recently, minimally invasive ablation methods have evolved significantly over the last decades, staging systems continue to evolve along the way. The 40-year-old Robson classification has been replaced with the TNM classification of RCC, because the latter adapts more easily to changing patterns of diagnosis and therapy. Modern cross-sectional imaging methods, such as multidetector-row computed tomography (MDCT), and magnetic resonance imaging (MRI), perform highly in T-staging of local tumor extent and M-staging of distant metastasis. However, both MDCT and MRI perform poorly in N-staging of lymphadenopathy. At present, 18-F-desoxy-glucose positron emission tomography (FDG-PET) appears to be unreliable in the detection of RCC and its metastasis. This overview of current radiological and surgical literature attempts to describe how modern staging systems for RCC are organized, and which radiological and surgical developments currently influence the way in which primary staging and prognosis of RCC depend on one another. |
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Authors:
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Ullrich G Mueller-Lisse; Ulrike L Mueller-Lisse; Thomas Meindl; Eva Coppenrath; Christoph Degenhart; Anno Graser; Michael Scherr; Maximilian F Reiser |
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Publication Detail:
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Type: Journal Article; Review Date: 2007-02-22 |
Journal Detail:
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Title: European radiology Volume: 17 ISSN: 0938-7994 ISO Abbreviation: Eur Radiol Publication Date: 2007 Sep |
Date Detail:
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Created Date: 2007-08-16 Completed Date: 2007-12-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 2268-77 Citation Subset: IM |
Affiliation:
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Department of Clinical Radiology, Ludwig Maximilian University of Munich, Ziemssenstrasse 1, 80336 München, Germany. ullrich.mueller-lisse@med.uni-muenchen.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Carcinoma, Renal Cell
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pathology* Contrast Media Humans Kidney Neoplasms / pathology* Magnetic Resonance Imaging / methods Neoplasm Metastasis Neoplasm Staging / methods* Prognosis Survival Analysis Tomography, Emission-Computed / methods Tomography, X-Ray Computed / methods |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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