| Staging of colon cancer: whole-body MRI vs. whole-body PET-CT--initial clinical experience. | |
| | |
MedLine Citation:
|
PMID: 18373114 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: To assess the accuracy of whole-body MR imaging (WB-MRI) in comparison with whole-body [18(F)]-2-fluoro-2-deoxy-D-glucose (FDG) PET-CT in staging patients with diagnosed colorectal carcinoma (CRC). METHODS: Twenty consecutive patients with previously diagnosed CRC underwent WB-MRI (3T) and PET-CT for staging of lymph node (N) and distant metastases (M). Evaluation was done according to the American Joint Committee on Cancer Staging Criteria. MR images were evaluated by two radiologists while PET-CT images by one radiologist and one nuclear medicine physician. Histology and/or a clinical follow-up of 3-6 months served as standard of reference. RESULTS: Lymph node involvement was determined in 10/20 cases as N-positive in WB-MRI and in 15/20 in PET-CT. M-stage was evaluated for liver metastases (27 lesions in 15 patients with WB-MRI, 23/15 patients with PET-CT), lung (19/5 patients with WB-MRI, 25/7 patients with PET-CT), and bone (9/3 patients with WB-MRI, 9/3 patients with PET-CT). Two patients showed peritoneal implants and three patients demonstrated local recurrence at the surgery site on both modalities. No brain metastases were found. CONCLUSIONS: WB-MRI is a feasible method for examining colon cancer patients but cannot displace the present role of PET-CT. |
| | |
Authors:
|
Ettore Squillaci; Guglielmo Manenti; Stefano Mancino; Carmelo Cicciò; Ferdinando Calabria; Roberta Danieli; Orazio Schillaci; Giovanni Simonetti |
Related Documents
:
|
17148724 - Diagnostic accuracy of colorectal cancer staging with whole-body pet/ct colonography. 17165434 - Value of whole body 18fdg-pet to identify the active site of gestational trophoblastic ... 16280234 - Pet/ct in the evaluation of patients with squamous cell cancer of the head and neck. 17018304 - Diagnostic value of multidetector row ct in rectal cancer staging: comparison of multip... 21799484 - Synthesis of magnetic resonance-, x-ray- and ultrasound-visible alginate microcapsules ... 21555104 - Clinical application of a 3d ultrasound-guided prostate biopsy system. |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
|
Title: Abdominal imaging Volume: 33 ISSN: 1432-0509 ISO Abbreviation: Abdom Imaging Publication Date: 2008 Nov-Dec |
Date Detail:
|
Created Date: 2008-11-25 Completed Date: 2009-02-10 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9303672 Medline TA: Abdom Imaging Country: United States |
Other Details:
|
Languages: eng Pagination: 676-88 Citation Subset: IM |
Affiliation:
|
Department of Diagnostic and Molecular Imaging, Interventional Radiology and Radiotherapy, University Policlinic Tor Vergata, University of Rome, Tor Vergata, Viale Oxford, 81, Rome, Italy. ettoresquillaci@tiscali.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Bone and Bones / pathology, radiography Colonic Neoplasms / pathology* Contrast Media / diagnostic use Feasibility Studies Female Fluorodeoxyglucose F18 / diagnostic use Follow-Up Studies Humans Image Processing, Computer-Assisted / methods Liver / pathology, radiography Lung / pathology, radiography Lymph Nodes / pathology, radiography Lymphatic Metastasis Magnetic Resonance Imaging / methods* Male Middle Aged Neoplasm Metastasis Neoplasm Staging Observer Variation Positron-Emission Tomography / methods* Radiopharmaceuticals / diagnostic use Reproducibility of Results Tomography, X-Ray Computed / methods* Whole Body Imaging / methods* |
| Chemical | |
Reg. No./Substance:
|
0/Contrast Media; 0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Diversity of bacterial communities in container habitats of mosquitoes.
Next Document: Detection of hepatocellular carcinoma by CT during arterial portography using a cone-beam CT technol...