Document Detail

Stable isotope tracers and the determination of fuel fluxes in newborn infants.
MedLine Citation:
PMID:  3327537     Owner:  NLM     Status:  MEDLINE    
After birth, newborns adapt from the in utero situation of a continuous fuel supply to the postnatal situation of feeding and fasting periods. In order to maintain adequate fluxes of energetic substrates to their various organs and tissues, neonates must rapidly activate the release of glucose, free fatty acids and ketone bodies into the blood stream. This review will summarize some of the techniques and results available today regarding the in vivo kinetics of an energetic substrate in early postnatal life: the rate of production of this substrate, the overall rate of its uptake by the tissues, its rate of oxidation and contribution to the total caloric demand, the rate of conversion of a precursor into this substrate.
P F Bougnères
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Biology of the neonate     Volume:  52 Suppl 1     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1987  
Date Detail:
Created Date:  1988-05-10     Completed Date:  1988-05-10     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  87-96     Citation Subset:  IM    
U 188 INSERM, Service d'Endocrinologie Pédiatrique, Hôpital Saint-Vincent-de-Paul, Paris, France.
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MeSH Terms
Energy Metabolism*
Fatty Acids / metabolism
Glucose / metabolism
Infant, Newborn / metabolism*
Isotopes / diagnostic use
Ketone Bodies / metabolism
Reg. No./Substance:
0/Fatty Acids; 0/Isotopes; 0/Ketone Bodies; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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