Document Detail


Stable isotope labeling of entire Bacillus atrophaeus spores and vegetative cells using bioaerosol mass spectrometry.
MedLine Citation:
PMID:  15858989     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Single vegetative cells and spores of Bacillus atrophaeus, formerly Bacillus subtilis var. niger, were analyzed using bioaerosol mass spectrometry. Key biomarkers were identified from organisms grown in 13C and 15N isotopically enriched media. Spore spectra contain peaks from dicipolinate and amino acids. The results indicate that compounds observed in the spectra correspond to material from the spore's core and not the exosporium. Standard compounds and mixtures were analyzed for comparison. The biomarkers for vegetative cells were clearly different from those of the spores, consisting mainly of phosphate clusters and amino acid fragments.
Authors:
Gregg A Czerwieniec; Scott C Russell; Herbert J Tobias; Maurice E Pitesky; David P Fergenson; Paul Steele; Abneesh Srivastava; Joanne M Horn; Matthias Frank; Eric E Gard; Carlito B Lebrilla
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Analytical chemistry     Volume:  77     ISSN:  0003-2700     ISO Abbreviation:  Anal. Chem.     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-04-29     Completed Date:  2007-01-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370536     Medline TA:  Anal Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1081-7     Citation Subset:  IM    
Affiliation:
Department of Chemistry, University of California, Davis, California 95616, USA.
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MeSH Terms
Descriptor/Qualifier:
Aerosols
Amino Acids / analysis
Bacillus subtilis / chemistry*
Biological Markers
Isotope Labeling*
Mass Spectrometry / methods*
Spores, Bacterial / chemistry*
Chemical
Reg. No./Substance:
0/Aerosols; 0/Amino Acids; 0/Biological Markers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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