Document Detail

Stable angina--who needs revascularisation?
MedLine Citation:
PMID:  17357474     Owner:  NLM     Status:  MEDLINE    
In the UK, about 5% of men and 3% of women have, or have had, angina. Also, estimates suggest that, each year, around 340,000 people present with the symptom for the first time. Characterised by pain or discomfort in the chest, angina is usually caused by atherosclerotic coronary artery disease and so carries an increased risk of cardiovascular complications such as myocardial infarction and death from coronary heart disease (CHD). In stable angina, the symptoms are induced by exertion, reflecting the limitation of blood supply through the narrowed arteries and the resulting myocardial ischaemia. The condition is not only potentially distressing, but may also limit daily function and quality of life. To address these problems and the elevated cardiovascular risk, standard management includes lifestyle measures (e.g. physical activity without excessive exertion, stopping smoking, weight control); tackling other cardiovascular risk factors (e.g. raised blood pressure, diabetes mellitus); and medication to control angina (e.g. nitrates, beta-blockers, calcium antagonists) and to reduce overall cardiovascular risk (e.g. aspirin, statin therapy). Where such non-invasive measures alone are inadequate, revascularisation (restoration of adequate blood supply to the heart muscle) by using coronary artery bypass graft (CABG) surgery or percutaneous coronary intervention (PCI) may also be needed. Here we discuss methods for, and difficulties in, assessing patients who present with suspected stable angina to identify those who could benefit from revascularisation.
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Drug and therapeutics bulletin     Volume:  45     ISSN:  0012-6543     ISO Abbreviation:  Drug Ther Bull     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-03-15     Completed Date:  2007-04-26     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0112037     Medline TA:  Drug Ther Bull     Country:  England    
Other Details:
Languages:  eng     Pagination:  12-6     Citation Subset:  IM    
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MeSH Terms
Angina Pectoris / diagnosis,  etiology,  therapy*
Myocardial Revascularization*
Patient Selection
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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