Document Detail

Stabilizing Effects of a Particulate Demineralized Bone Matrix in the L4 Interbody Space with and without PEEK Cage - A Literature Review and Preliminary Results of a Cadaveric Biomechanical Study.
MedLine Citation:
PMID:  25014862     Owner:  NLM     Status:  Publisher    
We reviewed the biological elements supporting the usefulness of a specifically designed particulate form of demineralized bone matrix (DBM) with spinal fusion, and report some limitations of its use described in the medical literature and in the interbody space using a cadaveric biomechanical model. A literature review and description of the techniques used to augment spinal fusion are presented, including a more thorough review of recent findings of cadaveric biomechanical flexibility studies using DBM alone at different percentage fills of the existing disc space and DBM with a polyetheretherketone (PEEK) interbody cage. The need for DBM was established by reviewing limitations of autografts and allografts in spinal fusion. Demineralized bone matrix used alone did not increase stability post discectomy at L4-L5, but was demonstrated to exhibit satisfactory stability when used with a PEEK interbody cage. There may be a future role for DBM that hardens and fills disc space more rigidly, overcoming this limitation to its use.
C Bruce; K R Chin; V Cumming; N R Crawford
Publication Detail:
Journal Detail:
Title:  The West Indian medical journal     Volume:  62     ISSN:  0043-3144     ISO Abbreviation:  West Indian Med J     Publication Date:  2013 Nov 
Date Detail:
Created Date:  2014-7-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417410     Medline TA:  West Indian Med J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  748-751     Citation Subset:  -    
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