Document Detail


Stability of transcription complexes on class II genes.
MedLine Citation:
PMID:  2494433     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Commitment of a TATA box-driven class II gene to transcription requires binding of only one transcription factor, TFIID. Additional factors (TFIIB, TFIIE, and RNA polymerase II) do not remain associated with the TFIID-promoter complex during the course of transcription. This indicates that there are two intermediates along the transcription reaction pathway which may be potential targets for the regulation of gene expression.
Authors:
M W Van Dyke; M Sawadogo; R G Roeder
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Molecular and cellular biology     Volume:  9     ISSN:  0270-7306     ISO Abbreviation:  Mol. Cell. Biol.     Publication Date:  1989 Jan 
Date Detail:
Created Date:  1989-05-01     Completed Date:  1989-05-01     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  8109087     Medline TA:  Mol Cell Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  342-4     Citation Subset:  IM    
Affiliation:
Laboratory of Biochemistry and Molecular Biology, Rockefeller University, New York, New York 10021.
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MeSH Terms
Descriptor/Qualifier:
Adenoviridae
DNA, Viral / analysis
DNA-Binding Proteins / metabolism
Genes, MHC Class II*
Humans
Promoter Regions, Genetic*
RNA Polymerase II / metabolism
Transcription Factors / genetics,  metabolism
Transcription, Genetic*
Grant Support
ID/Acronym/Agency:
CA 42567/CA/NCI NIH HHS; GM 38212/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/DNA, Viral; 0/DNA-Binding Proteins; 0/Transcription Factors; EC 2.7.7.-/RNA Polymerase II
Comments/Corrections

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