Document Detail

Stability of oxygen transmissibility during ischemia.
MedLine Citation:
PMID:  6122173     Owner:  NLM     Status:  MEDLINE    
Simultaneous measurements of oxygen availability (O2a) and partial pressure (PO2) were made by the double noble metal electrode system designed by Erdmann and Krell in an attempt to monitor the oxygen transmissibility (Dk) with respect to time before and after ischemic episodes in the brain cortex. Available current equations can appropriately describe the performance of the electrode in a homogeneous nonconsuming medium, and with some experimental error this electrode system can be used to estimate oxygen transmissibility changes in the brain based on the different characteristics of the O2a (rod-type, flush-ended bare tip) and the PO2 (rod-type, recessed tip) cathodes. Our method monitors the oxygen transmissibility within the diffusion sphere of the bare tip as the ratio of the currents related to O2a and PO2. We find with this system that even prolonged global cerebral ischemia does not alter the oxygen transmissibility of the brain tissue. Therefore, alternation of the oxygen transmissibility can not be a contributing factor to postischemic cerebral malfunction.
A Eke; E Strong; J H Halsey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurological research     Volume:  3     ISSN:  0161-6412     ISO Abbreviation:  Neurol. Res.     Publication Date:  1981  
Date Detail:
Created Date:  1982-06-14     Completed Date:  1982-06-14     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7905298     Medline TA:  Neurol Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  211-28     Citation Subset:  IM    
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MeSH Terms
Brain Ischemia / metabolism*
Cerebral Cortex / analysis*
Oxygen / analysis*
Polarography / instrumentation
Time Factors
Reg. No./Substance:

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