Document Detail

Stabilities of free and complexed human immunodeficiency virus p24 antigens during short- and long-term storage.
MedLine Citation:
PMID:  9276428     Owner:  NLM     Status:  MEDLINE    
By the standard p24 assay there was a 25 to 27% decrease in free p24 antigen in serum after storage at 4 degrees C over 14 days but no loss at -70 degrees C. There was no loss at either temperature by the immune complex dissociation (ICD) procedure. Furthermore, there was no significant loss of detectable p24 in serum by either the ICD or the standard p24 assay after 700 days of storage at -70 degrees C.
M Arens; W Meyer; D Brambilla; J Bremer; S Fiscus; B Griffith; S Hammer; R Hodinka; W Kabat; B Yen-Lieberman; L Myers; P Reichelderfer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical microbiology     Volume:  35     ISSN:  0095-1137     ISO Abbreviation:  J. Clin. Microbiol.     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1997-10-17     Completed Date:  1997-10-17     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7505564     Medline TA:  J Clin Microbiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2413-6     Citation Subset:  IM; X    
Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
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MeSH Terms
Antigen-Antibody Complex / immunology,  physiology
Cryopreservation / methods*
HIV Core Protein p24 / immunology,  physiology*
HIV-1 / immunology,  physiology*
Prospective Studies
Specimen Handling / methods*
Reg. No./Substance:
0/Antigen-Antibody Complex; 0/HIV Core Protein p24
Comment In:
J Clin Microbiol. 1998 Mar;36(3):855   [PMID:  9508335 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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