| St. Jude Medical prosthesis: valve-related deaths and complications. | |
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MedLine Citation:
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PMID: 3496058 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Despite the hemodynamic improvement in cardiac valve prostheses, valve-related deaths and complications have remained a substantial source of morbidity and mortality. This follow-up study was carried out in April, 1986, in a group of 816 patients who received 876 St. Jude Medical prostheses between October, 1977, and October, 1984. One hundred fifty-five patients (37%) of the 422 having aortic valve replacement (AVR) and 88 (29%) of the 300 having mitral valve replacement (MVR) had concomitant coronary artery bypass grafting, and 94 patients (12%) had miscellaneous procedures performed in addition to valve replacement. Sixty-three patients died within the operative period, an operative mortality of 7.7%. Follow-up was complete for 98% of the patients; the mean follow-up was 42 months. At that time, 87 more patients had died, a late mortality of 11.9%. There were 13 valve-related deaths (4 in the AVR group, 7 in the MVR group, and 2 in the miscellaneous group); the causes of death were thromboembolism (7), anticoagulant-related hemorrhage (2), valve thrombosis (2), prosthetic valve endocarditis (1), and perivalvular leak (1). There were 37 thromboembolic episodes (1.78/100 patient-years) and 67 anticoagulant-related hemorrhages (3.22/100 patient-years), 46% of which necessitated transfusion. The incidence of valve thrombosis was 0.6% (4 patients). Perivalvular leak and prosthetic valve endocarditis occurred in 7 patients (1.0%) and 5 patients (0.7%), respectively. Reoperation was carried out in 6 patients (0.8%), but only for perivalvular leak. There were no deaths, no complications, and no clinical evidence of malfunction of the prosthetic valve.(ABSTRACT TRUNCATED AT 250 WORDS) |
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Authors:
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K V Arom; D M Nicoloff; T E Kersten; W G Lindsay; W F Northrup |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 43 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 1987 Jun |
Date Detail:
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Created Date: 1987-07-08 Completed Date: 1987-07-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 591-8 Citation Subset: AIM; IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Aortic Valve Child Child, Preschool Coronary Artery Bypass / adverse effects, mortality Female Follow-Up Studies Heart Valve Diseases / complications, mortality, surgery Heart Valve Prosthesis / adverse effects, mortality* Hemorrhage / epidemiology, mortality Humans Infant Male Middle Aged Mitral Valve Postoperative Complications / epidemiology, mortality* Thromboembolism / epidemiology, mortality |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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