Document Detail

St. Jude Medical and CarboMedics mechanical heart valves in the aortic position: comparison of long-term results.
MedLine Citation:
PMID:  16878617     Owner:  NLM     Status:  MEDLINE    
We designed this study to compare long-term results of St. Jude Medical and CarboMedics mechanical heart valves in the aortic position. We retrospectively analyzed the results of 174 consecutive patients who received either a St. Jude (n=80) or a CarboMedics (n=94) mechanical aortic valve from March 1992 through October 2004. The follow-up rate was 97.7%. The mean follow-up duration for the St. Jude group was 79.3 +/- 35.0 and for the CarboMedics group, 70.0 +/- 34.3 months. The cumulative follow-up was 523.8 and 530.1 patient-years, respectively The 30-day mortality rates for the St. Jude and CarboMedics patients were 1.3% and 3.2%, respectively. The actuarial survival rate for the St. Jude group at 138.0 +/- 4.7 months was 75.9% +/- 0.1% and for the CarboMedics group at 130.8 +/- 4.8 months was 69.8% +/- 0.1% (P=NS). There was no structural valve deterioration in either group. Freedom from thromboembolic events was 87.7% for the St. Jude group and 83.0% for the CarboMedics group (P=NS). Freedom from bleeding events for the St. Jude group was 93.6% and for the CarboMedics group, 89.7% (P=NS). The results obtained from this study indicate that standard St. Jude Medical and CarboMedics aortic valve prostheses offer similar excellent clinical performance. Definitive judgment must await trials that are extensive, randomized, and prospective.
Ozer Kandemir; Hilmi Tokmakoglu; Ulku Yildiz; Tevfik Tezcaner; A Cem Yorgancioglu; Lihan Gunay; Kaya Suzer; Yaman Zorlutuna
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital     Volume:  33     ISSN:  0730-2347     ISO Abbreviation:  Tex Heart Inst J     Publication Date:  2006  
Date Detail:
Created Date:  2006-08-01     Completed Date:  2006-09-21     Revised Date:  2013-06-07    
Medline Journal Info:
Nlm Unique ID:  8214622     Medline TA:  Tex Heart Inst J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  154-9     Citation Subset:  IM    
Department of Cardiovascular Surgery, Bayindir Hospital, Ankara, Turkey.
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MeSH Terms
Anticoagulants / therapeutic use
Aortic Valve*
Cause of Death
Heart Valve Prosthesis*
Middle Aged
Prosthesis Design
Retrospective Studies
Thromboembolism / epidemiology
Treatment Outcome
Warfarin / therapeutic use
Reg. No./Substance:
0/Anticoagulants; 81-81-2/Warfarin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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