Document Detail

St. Anthony's fire (ergotamine induced leg ischemia)--a case report and review of the literature.
MedLine Citation:
PMID:  11386387     Owner:  NLM     Status:  MEDLINE    
Ergotism, once an epidemic disease, is now a rare disorder. The most common manifestation is acute peripheral ischemia due to vasospasm, with an incidence of 0.001%. We report a case of a middle-age woman who presented with ergotamine-induced leg ischemia, due to chronic use of ergotamine-containing medications for migraine headaches. The diagnosis was confirmed with arteriography results, and she responded well to vasodilator therapy. The pharmacology, clinical presentation, diagnostic approach, and therapy of ergotism are reviewed.
E G Zavaleta; B B Fernandez; M K Grove; M D Kaye
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Angiology     Volume:  52     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-06-01     Completed Date:  2001-06-14     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  349-56     Citation Subset:  IM    
Department of Internal Medicine, The Cleveland Clinic Florida, Fort Lauderdale 33309, USA.
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MeSH Terms
Ergot Alkaloids / pharmacology
Ergotism / complications*
Ischemia / drug therapy,  etiology*,  radiography
Leg / blood supply*
Middle Aged
Vasoconstriction / drug effects
Reg. No./Substance:
0/Ergot Alkaloids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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