Document Detail

Squamous metaplasia of the tracheal epithelium in children.
MedLine Citation:
PMID:  941106     Owner:  NLM     Status:  MEDLINE    
Thirty-seven (1-6%) tracheas from 2170 children showed squamous metaplasia. (Cases with tracheo-oesophageal fistula and congenital heart disease were excluded). The metaplasia extended into the bronchi in 15 cases. Features of pulmonary retention were present in seven cases. Respiratory infection, probably viral, seemed to be the most significant causative factor in 20 children, including those with cystic fibrosis. Tracheal instrumentation was a possible factor in 11 cases but oxygen therapy alone did not seem important. The metaplasia was almost certainly congenital in one child and probably in two others but no stillborn infants showed metaplasia. In many children the metaplasia seemed to be due to a combination of factors.
A Mithal; J L Emery
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Thorax     Volume:  31     ISSN:  0040-6376     ISO Abbreviation:  Thorax     Publication Date:  1976 Apr 
Date Detail:
Created Date:  1976-09-25     Completed Date:  1976-09-25     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0417353     Medline TA:  Thorax     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  167-71     Citation Subset:  IM    
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MeSH Terms
Child, Preschool
Epithelium / pathology
Infant, Newborn
Intubation, Intratracheal / adverse effects
Metaplasia / etiology,  pathology
Oxygen Inhalation Therapy
Pulmonary Alveoli / pathology
Trachea / pathology
Tracheal Diseases / pathology*
Tracheotomy / adverse effects
Virus Diseases / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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