Document Detail

Squamous cell carcinoma with presence of poxvirus-like inclusions in the foot of a pink-backed pelican (Pelecanus rufescens).
MedLine Citation:
PMID:  19468940     Owner:  NLM     Status:  MEDLINE    
Squamous cell carcinoma (SCC) or avian keratoacanthoma is a neoplastic skin lesion of unknown aetiology that has been well described in birds. Some studies have reported that poxviruses may contribute to the onset of SCC. Here we describe a case of SCC on the underside of a pelican's foot. Histologically, the tumour consisted of irregular cords of pleomorphic epithelial cells that invaded the adjacent tissues. Additionally, keratinized epithelial cells and moderate numbers of keratin pearls were observed. Intracytoplasmic inclusions, a characteristic of this virus, were observed in some of these cells, and viral particles were characterized by electron microscopy. Although the aetiology of the carcinoma in this case may have been secondary to chronic focal trauma, the possibility of a latent or chronic form of fowlpox should be considered in the pathogenesis of the lesion.
Stefano Pesaro; Barbara Biancani; Gabriele Fabbrizi; Giacomo Rossi
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Avian pathology : journal of the W.V.P.A     Volume:  38     ISSN:  1465-3338     ISO Abbreviation:  Avian Pathol.     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-05-26     Completed Date:  2009-08-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8210638     Medline TA:  Avian Pathol     Country:  England    
Other Details:
Languages:  eng     Pagination:  229-31     Citation Subset:  IM    
Department of Veterinary Science, University of Camerino, Matelica, Italy.
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MeSH Terms
Bird Diseases / pathology*,  virology
Carcinoma, Squamous Cell / pathology,  veterinary*,  virology
Foot Diseases / pathology,  veterinary*,  virology
Fowlpox virus / ultrastructure*
Inclusion Bodies / pathology*
Microscopy, Immunoelectron
Skin Neoplasms / pathology,  veterinary*,  virology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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