| Squamous cell carcinoma of the vulva in a virgin patient with Turner syndrome. | |
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MedLine Citation:
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PMID: 21998766 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Two types of gynecologic tumors are commonly described in the Turner syndrome, the first one is gonadoblastoma, which occurs in patients with Y chromosome abnormalities, and the second one is endometrial carcinoma which is mostly related with exogenous estrogen usage. Here, we describe an extremely rare case of squamous cell carcinoma of the vulva in a virgin woman with Turner syndrome. A 35-years old single, virgin woman referred to our Oncology Department with warty, necrotized, exophytic 6-7 cm vulvar mass. She had a history of primary amenorrhea and mosaic Turner syndrome was determined in her karyotype analysis. Biopsy specimen of the vulvar mass revealed squamous cell carcinoma of the vulva, and total vulvectomy with inguinal femoral lymphadenectomy was performed. The postoperative course was uneventful and there has been no recurrence of the disease up to date. Women with Turner syndrome have streak ovaries that produce very low estrogen and the squamous cell carcinoma of the vulva may have developed at an early age with Turner syndrome because of this low estrogen value similar to postmenopausal women. The current case is a special case due to its age of occurrence, virgin and Turner syndrome status. |
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Authors:
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Omer Lutfi Tapisiz; Onur Topcu; Tayfun Gungor; Bulent Ozdal; Levent Sirvan; Ahmet Yesilyurt |
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Publication Detail:
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Type: Journal Article Date: 2011-09-28 |
Journal Detail:
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Title: Journal of gynecologic oncology Volume: 22 ISSN: 2005-0399 ISO Abbreviation: J Gynecol Oncol Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-10-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101483150 Medline TA: J Gynecol Oncol Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 211-3 Citation Subset: - |
Affiliation:
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Department of Gynecologic Oncology, Dr. Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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