Document Detail


Squamous cell carcinoma of the renal pelvis with sarcomalike stroma: a light and electron microscopic study with immunohistochemical analysis.
MedLine Citation:
PMID:  2446084     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Primary neoplasms of the renal pelvis are rare. Most are malignant, and most of these are transitional cell carcinomas. We report the unusual occurrence of a squamous cell carcinoma with sarcomatoid stroma arising from the renal pelvic mucosa in a patient with renal lithiasis. Immunohistochemical stains for keratin intermediate filaments failed to demonstrate their presence in the spindle cell portion of the tumor. Transmission electron microscopic study did not reveal structures of an epithelial nature in these same cells. Our findings support the contention that the spindle cells of the stroma are not squamous in nature, but represent either a reactive or a neoplastic transformation of these underlying stromal elements.
Authors:
J Goldstein; M Mozes; L Lismer; I Levin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of surgical oncology     Volume:  36     ISSN:  0022-4790     ISO Abbreviation:  J Surg Oncol     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1987-12-28     Completed Date:  1987-12-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0222643     Medline TA:  J Surg Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  188-92     Citation Subset:  IM    
Affiliation:
Institute of Pathology, Soroka University Hospital, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
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MeSH Terms
Descriptor/Qualifier:
Carcinoma, Squamous Cell / metabolism,  pathology*
Epithelium / metabolism,  ultrastructure
Humans
Immunohistochemistry
Keratins / metabolism
Kidney Calculi / metabolism,  pathology
Kidney Neoplasms / metabolism,  pathology*
Kidney Pelvis*
Male
Microscopy, Electron
Middle Aged
Necrosis
Sarcoma / metabolism,  pathology*
Chemical
Reg. No./Substance:
68238-35-7/Keratins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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