Document Detail

Squamous cell carcinoma arising in a ciliated hepatic foregut cyst: case report and literature review.
MedLine Citation:
PMID:  19410383     Owner:  NLM     Status:  MEDLINE    
We report a case of squamous cell carcinoma arising in a ciliated hepatic foregut cyst (CHFC) in the left lobe of the liver in a 60-year-old woman. Gross examination revealed an irregular, partially encapsulated, smooth tumor mass with multiple cystic areas, 3-5mm in size. Microscopically, the lining of the microcysts was composed of ciliated columnar epithelium with scattered goblet cells. Multiple foci of squamous metaplasia of the columnar epithelium were observed, which showed areas with dysplastic changes and other areas with carcinomatous transformation. Our case also showed an inconspicuous or absent smooth muscle layer. This case suggests that CHFC deserves careful clinical follow-up and differential diagnosis to exclude malignant transformation. Total surgical excision of the cyst is recommended.
Xiangsheng Zhang; Zhen Wang; Yanjun Dong
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-05-02
Journal Detail:
Title:  Pathology, research and practice     Volume:  205     ISSN:  1618-0631     ISO Abbreviation:  Pathol. Res. Pract.     Publication Date:  2009  
Date Detail:
Created Date:  2009-06-05     Completed Date:  2009-08-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7806109     Medline TA:  Pathol Res Pract     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  498-501     Citation Subset:  IM    
Department of Pathology, Binzhou Medical College, Shandong 256603, China.
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MeSH Terms
Carcinoma, Squamous Cell / pathology*,  surgery
Cysts / pathology*,  surgery
Epithelial Cells / pathology
Goblet Cells / pathology
Liver Diseases / pathology*,  surgery
Liver Neoplasms / pathology*,  surgery
Middle Aged
Precancerous Conditions / pathology*,  surgery
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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