Document Detail

Squamous cell carcinoma arising from chronic lymphedema: case report and review of the literature.
MedLine Citation:
PMID:  20512280     Owner:  NLM     Status:  MEDLINE    
CONTEXT: Squamous cell carcinoma arising from chronic lymphedema has only been reported in the literature 11 times (12 cases). Some aspects of its pathogenesis remain unclear and, for the first time, attention has been drawn to epidemiological data.
CASE REPORT: A 90-year-old white female with chronic unilateral lower-limb lymphedema, secondary to trauma 20 years earlier, presented with a three-month history of a vegetating cutaneous lesion. There had not been any previous local ulceration. The tumor was completely excised and the histopathological analysis showed that it was an infiltrating squamous cell carcinoma. A literature review in the Medline (Medical Literature Analysis and Retrieval System Online) and Lilacs (Literatura Latino-Americana e do Caribe em Ciências da Saúde) databases using the MeSH (Medical Subject Heading) terms "Carcinoma, Squamous Cell" AND "Lymphedema" identified 112 references and found 12 similar case reports.
Carlos Augusto Gomes; Camila Beatriz Silva Magalhães; Cleber Soares; Rodrigo de Oliveira Peixoto
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  São Paulo medical journal = Revista paulista de medicina     Volume:  128     ISSN:  1806-9460     ISO Abbreviation:  Sao Paulo Med J     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-05-31     Completed Date:  2010-12-17     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  100897261     Medline TA:  Sao Paulo Med J     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  42-4     Citation Subset:  IM    
Department of Surgery, Hospital Universitário, Universidade Federal de Juiz de Fora.
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MeSH Terms
Aged, 80 and over
Carcinoma, Squamous Cell / etiology*,  surgery
Chronic Disease
Lymphedema / complications*
Skin Neoplasms / etiology*,  surgery

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