| Squamous carcinoma of the foot arising in association with long-standing verrucous hyperplasia in a patient with congenital lymphedema. | |
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MedLine Citation:
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PMID: 6540138 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A patient is reported with congenital lymphedema who developed a squamous cell carcinoma on his affected foot. Parallels are drawn between the development of a squamous cell carcinoma with condylomatous and spindle cell features arising in a setting of long-standing verrucous hyperplasia, as seen in this patient, and the well-recognized phenomenon of angiosarcoma occurring in areas of lymphangiomatous proliferation in patients with chronic lymphedema. The importance of a random genetic mutation occurring in hyperplastic tissue in an immunologically privileged site is discussed. Additional consideration is given, in the current case, to the possibility of viral oncogenesis and the role of ulceration as a promoter factor. |
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Authors:
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J I Epstein; G Mendelsohn |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Cancer Volume: 54 ISSN: 0008-543X ISO Abbreviation: Cancer Publication Date: 1984 Sep |
Date Detail:
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Created Date: 1984-09-06 Completed Date: 1984-09-06 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0374236 Medline TA: Cancer Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 943-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Carcinoma, Squamous Cell
/
complications*,
pathology,
surgery Foot Diseases / complications*, pathology, surgery Hemangiosarcoma / complications, pathology Humans Hyperplasia Lymphedema / complications*, congenital, pathology Male Middle Aged Skin Neoplasms / complications*, pathology, surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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