Document Detail


Squamous carcinoma of the foot arising in association with long-standing verrucous hyperplasia in a patient with congenital lymphedema.
MedLine Citation:
PMID:  6540138     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A patient is reported with congenital lymphedema who developed a squamous cell carcinoma on his affected foot. Parallels are drawn between the development of a squamous cell carcinoma with condylomatous and spindle cell features arising in a setting of long-standing verrucous hyperplasia, as seen in this patient, and the well-recognized phenomenon of angiosarcoma occurring in areas of lymphangiomatous proliferation in patients with chronic lymphedema. The importance of a random genetic mutation occurring in hyperplastic tissue in an immunologically privileged site is discussed. Additional consideration is given, in the current case, to the possibility of viral oncogenesis and the role of ulceration as a promoter factor.
Authors:
J I Epstein; G Mendelsohn
Related Documents :
7503668 - Basaloid-squamous cell carcinoma of the bronchus. report of a case with review of the l...
9622708 - Metastatic laryngeal basaloid squamous cell carcinoma simulating primary small cell car...
17018598 - Squamous cell carcinoma related oncogene/dcun1d1 is highly conserved and activated by a...
17239268 - Primary squamous cell carcinoma of the breast: value of positron emission tomography sc...
22900808 - Hereditary breast and ovarian cancer: research on how women respond to genetic testing.
24133538 - Chromoblastomycosis - a clinical mimic of squamous carcinoma.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cancer     Volume:  54     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1984 Sep 
Date Detail:
Created Date:  1984-09-06     Completed Date:  1984-09-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  943-7     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Carcinoma, Squamous Cell / complications*,  pathology,  surgery
Foot Diseases / complications*,  pathology,  surgery
Hemangiosarcoma / complications,  pathology
Humans
Hyperplasia
Lymphedema / complications*,  congenital,  pathology
Male
Middle Aged
Skin Neoplasms / complications*,  pathology,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Coexistence of adenocarcinoma and choriocarcinoma in the sigmoid colon.
Next Document:  Lymphadenopathic type of Kaposi's sarcoma presenting with generalized petechial hemorrhages. A case ...