Document Detail


Squamotous-type sarcomatoid carcinoma of the lung with rhabdomyosarcomatous components.
MedLine Citation:
PMID:  22531538     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Lung carcinosarcoma is an infrequently biphasic tumor composed of carcinomatous and sarcomatous components. It is divided into endobronchial (squamous-type) and peripheral (glandular type) categories. The carcinomatous component is usually a squamous carcinoma, and the sarcomatous component usually resembles a fibrosarcoma or a malignant fibrous histiocytoma. The presence of rhabdomyoblastic differentiation in such neoplasms is exceedingly rare. There are strong associations with smoking and asbestosis. In this study, we describe a unique case of a 43-year-old man with a 75 packet/year smoking history in whom a rare mixed malignant tumor of the lung was diagnosed and treated by left pneumonectomy. Histological examination of the resected specimen showed squamous cell carcinoma and rhabdomyosarcoma components. Although rare, the association of a sarcomatoid carcinoma of the lung with squamous cell carcinoma and rhabdomyosarcomatous component is possible and should be kept in mind when dealing with these unusual tumors.
Authors:
Figen Turk; Gokhan Yuncu; Ferda Bir; Gokhan Ozturk; Yasin Ekinci
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cancer research and therapeutics     Volume:  8     ISSN:  1998-4138     ISO Abbreviation:  J Cancer Res Ther     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-04-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101249598     Medline TA:  J Cancer Res Ther     Country:  India    
Other Details:
Languages:  eng     Pagination:  148-50     Citation Subset:  IM    
Affiliation:
Department of Thoracic Surgery, Pamukkale University Faculty of Medicine, Denizli, Turkey.
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