Document Detail


Squamoid eccrine ductal carcinoma: a case report and review of the literature.
MedLine Citation:
PMID:  20010402     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eccrine ductal carcinoma is a rare adnexal tumor. Squamoid eccrine ductal carcinoma (SEDC) represents an exceptionally rare variant with only 6 cases reported to date. This neoplasm is deeply infiltrative and may provide a diagnostic challenge in superficial shave biopsies of skin. We present a case of SEDC in an immunocompromised patient, who, after an initial shave biopsy for diagnostic purposes, underwent a complete excision of his tumor by Mohs micrographic surgery. A combined histologic and immunohistochemical approach is necessary to identify and confirm the unique characteristics of SEDC. Because this cancer is very rare and little is known about its biologic behavior, optimal diagnostic and treatment guidelines need to be developed.
Authors:
Elina Terushkin; David J Leffell; Tanya Futoryan; Shawn Cowper; Rossitza Lazova
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American Journal of dermatopathology     Volume:  32     ISSN:  1533-0311     ISO Abbreviation:  Am J Dermatopathol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-26     Completed Date:  2010-07-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911005     Medline TA:  Am J Dermatopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  287-92     Citation Subset:  IM    
Affiliation:
Edward Via Virginia College of Osteopathic Medicine, Blacksburg, VA, USA.
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MeSH Terms
Descriptor/Qualifier:
Carcinoma, Squamous Cell / chemistry,  pathology*,  surgery
Eccrine Glands / chemistry,  pathology*
Head and Neck Neoplasms / chemistry,  pathology*,  surgery
Humans
Immunocompromised Host
Male
Middle Aged
Mohs Surgery
Sweat Gland Neoplasms / chemistry,  pathology*,  surgery
Tumor Markers, Biological / analysis
Chemical
Reg. No./Substance:
0/Tumor Markers, Biological

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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