| Sputum eosinophilia in Churg-Strauss syndrome. | |
| | |
MedLine Citation:
|
PMID: 11601744 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Sputum induction (IS) can be used to study airway inflammation in asthmatics and other lung diseases. However, no data are available for patients with Churg-Strauss syndrome (CSS). A study was carried out to evaluate eosinophil counts and eosinophil cationic protein (ECP) levels in induced sputum during the follow-up of three patients with CSS. Induced sputum was carried out in 10 patients with corticosteroid-dependent asthma (used as a control group). Patients with CSS had significantly higher eosinophils percentages and ECP levels in sputum than those with stable corticosteroid-dependent asthma. During the follow-up, patients with CSS presented increased ECP levels sputum and eosinophils in sputum as well as increased blood eosinophils, despite their oral corticosteroid and immunosuppressive treatment. Eosinophil percentage in sputum and the total number of eosinophils in peripheral blood were more predictive of exacerbations of CSS than sputum ECP. |
| | |
Authors:
|
H Meziane; M L Maakel; I Vachier; J Bousquet; P Chanez |
Related Documents
:
|
11834644 - Oropharyngeal deglutition in stable copd. 16316874 - Relationship between peak expiratory flow rate and shoulders posture in healthy individ... 361794 - Response to corticosteroids in chronic bronchitis. 12324674 - Analysis of induced sputum in adults with asthma: identification of subgroup with isola... 2529164 - The use of two new coagulation probes for control of hemorrhage in laparoscopic liver b... 6157794 - Lithium carbonate in the treatment of cluster headaches. |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Respiratory medicine Volume: 95 ISSN: 0954-6111 ISO Abbreviation: Respir Med Publication Date: 2001 Oct |
Date Detail:
|
Created Date: 2001-10-16 Completed Date: 2001-11-01 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8908438 Medline TA: Respir Med Country: England |
Other Details:
|
Languages: eng Pagination: 799-801 Citation Subset: IM |
Affiliation:
|
Clinique des Maladies Respiratoires and INSERM U 454, Hospital Arnaud deVilleneuve, CHU Montpellier, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acute Disease Adult Asthma / drug therapy, immunology Blood Proteins / analysis Churg-Strauss Syndrome / drug therapy, immunology* Eosinophil Granule Proteins Eosinophils / immunology* Female Follow-Up Studies Glucocorticoids / therapeutic use Humans Leukocyte Count Male Middle Aged Pilot Projects Ribonucleases* Sputum / immunology* |
| Chemical | |
Reg. No./Substance:
|
0/Blood Proteins; 0/Eosinophil Granule Proteins; 0/Glucocorticoids; EC 3.1.-/Ribonucleases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Macrophages, neutrophils and tumour necrosis factor-alpha expression in bronchiectatic airways in vi...
Next Document: Delays in the diagnosis and treatment of hospitalized patients with smear-positive pulmonary tubercu...