Document Detail

Spreading pigmented actinic keratosis. An electron microscopic study.
MedLine Citation:
PMID:  2452605     Owner:  NLM     Status:  MEDLINE    
Spreading pigmented actinic keratosis is a rarely reported premalignant, pigmented, epidermal tumor that can be difficult to distinguish clinically from other benign and malignant pigmented lesions. In an attempt to determine the cause of clinical hyperpigmentation, seven lesions from five patients were examined by light microscopy. Three of these lesions were also examined using electron microscopy. Findings from these studies indicate that hyperpigmentation is due to enhanced melanosome formation and distribution and not to a melanocyte-keratinocyte melanosome transfer block.
S M Dinehart; R L Sanchez
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of dermatology     Volume:  124     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-06-09     Completed Date:  1988-06-09     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  680-3     Citation Subset:  AIM; IM    
Department of Dermatology, University of Texas Medical Branch, Galveston.
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MeSH Terms
Epidermis / pathology,  ultrastructure*
Keratosis / pathology*,  surgery
Melanocytes / pathology
Microscopy, Electron
Middle Aged
Skin Pigmentation
Reg. No./Substance:

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