| Spread of steroid-containing foam after intrarectal administration. | |
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MedLine Citation:
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PMID: 466209 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The spread of a steroid-containing foam from the rectum was studied in eight normal controls and eight patients with ulcerative colitis proved by biopsy. A standard dose of foam was labelled with technetium-99m adsorbed on to microspheres of Amberlite resin. Immediately after the foam was administered the extent of spread varied considerably, though in no instance did it extend beyond the rectosigmoid. Further scans at 120 and 240 minutes showed no further spread. It is concluded that a steroid-containing foam has a topical effect only on the rectal mucosa. |
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Authors:
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D J Hay; H Sharma; M H Irving |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: British medical journal Volume: 1 ISSN: 0007-1447 ISO Abbreviation: Br Med J Publication Date: 1979 Jun |
Date Detail:
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Created Date: 1979-10-26 Completed Date: 1979-10-26 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0372673 Medline TA: Br Med J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1751-3 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Anti-Inflammatory Agents / therapeutic use* Colitis, Ulcerative / drug therapy Enema / methods* Humans Hydrocortisone / administration & dosage, analogs & derivatives* Proctitis / drug therapy Rectum / radionuclide imaging |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 50-23-7/Hydrocortisone |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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