Document Detail


Sporulation in the budding yeast Saccharomyces cerevisiae.
MedLine Citation:
PMID:  22084423     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In response to nitrogen starvation in the presence of a poor carbon source, diploid cells of the yeast Saccharomyces cerevisiae undergo meiosis and package the haploid nuclei produced in meiosis into spores. The formation of spores requires an unusual cell division event in which daughter cells are formed within the cytoplasm of the mother cell. This process involves the de novo generation of two different cellular structures: novel membrane compartments within the cell cytoplasm that give rise to the spore plasma membrane and an extensive spore wall that protects the spore from environmental insults. This article summarizes what is known about the molecular mechanisms controlling spore assembly with particular attention to how constitutive cellular functions are modified to create novel behaviors during this developmental process. Key regulatory points on the sporulation pathway are also discussed as well as the possible role of sporulation in the natural ecology of S. cerevisiae.
Authors:
Aaron M Neiman
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Genetics     Volume:  189     ISSN:  1943-2631     ISO Abbreviation:  Genetics     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-15     Completed Date:  2012-03-01     Revised Date:  2013-06-27    
Medline Journal Info:
Nlm Unique ID:  0374636     Medline TA:  Genetics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  737-65     Citation Subset:  IM    
Affiliation:
Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York 11794-5215, USA. aaron.neiman@stonybrook.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Cycle
Cell Membrane / metabolism
RNA Processing, Post-Transcriptional
Saccharomyces cerevisiae / cytology,  genetics,  metabolism,  physiology*
Spores, Fungal / cytology,  genetics,  metabolism,  physiology*
Grant Support
ID/Acronym/Agency:
P01GM088297/GM/NIGMS NIH HHS; R01GM072540/GM/NIGMS NIH HHS
Comments/Corrections

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