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Spontaneously Resolving Periocular Erythema and Ciliary Madarosis Following Intra-arterial Chemotherapy for Retinoblastoma.
MedLine Citation:
PMID:  20844675     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
PURPOSE AND DESIGN: To describe an unusual clinical finding seen in children undergoing intra-arterial chemotherapy for retinoblastoma.
MATERIALS AND METHODS: A retrospective review of 69 eyes of 63 patients receiving intra-arterial chemotherapy over a 3-year period. Charts and photographs of 69 consecutive cases were reviewed, and data were collected on patients with clinical evidence of a hyperemic cutaneous periocular abnormality following the procedure.
RESULTS: A blanching erythematous and edematous patch was noted in the periocular region in 16% (11 of 69) of the children who received intraarterial chemotherapy. The plaque extended into the region of the supertrochlear and medial marginal artery distribution on the ipsilateral side of the intra-arterial chemotherapy. All patches of erythema spontaneously resolved within 3 months following completion of the intra-arterial chemotherapy.
CONCLUSION: Periocular erythema and swelling is a self-limited clinical finding associated with intra-arterial chemotherapy in a small number of patients.
Authors:
Brian Marr; Pierre Y Gobin; Ira J Dunkel; Scott E Brodie; David H Abramson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Middle East African journal of ophthalmology     Volume:  17     ISSN:  0975-1599     ISO Abbreviation:  Middle East Afr J Ophthalmol     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-09-16     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101521797     Medline TA:  Middle East Afr J Ophthalmol     Country:  India    
Other Details:
Languages:  eng     Pagination:  207-9     Citation Subset:  -    
Affiliation:
Ophthalmic Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
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