| Spontaneously Resolving Periocular Erythema and Ciliary Madarosis Following Intra-arterial Chemotherapy for Retinoblastoma. | |
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MedLine Citation:
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PMID: 20844675 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE AND DESIGN: To describe an unusual clinical finding seen in children undergoing intra-arterial chemotherapy for retinoblastoma. MATERIALS AND METHODS: A retrospective review of 69 eyes of 63 patients receiving intra-arterial chemotherapy over a 3-year period. Charts and photographs of 69 consecutive cases were reviewed, and data were collected on patients with clinical evidence of a hyperemic cutaneous periocular abnormality following the procedure. RESULTS: A blanching erythematous and edematous patch was noted in the periocular region in 16% (11 of 69) of the children who received intraarterial chemotherapy. The plaque extended into the region of the supertrochlear and medial marginal artery distribution on the ipsilateral side of the intra-arterial chemotherapy. All patches of erythema spontaneously resolved within 3 months following completion of the intra-arterial chemotherapy. CONCLUSION: Periocular erythema and swelling is a self-limited clinical finding associated with intra-arterial chemotherapy in a small number of patients. |
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Authors:
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Brian Marr; Pierre Y Gobin; Ira J Dunkel; Scott E Brodie; David H Abramson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Middle East African journal of ophthalmology Volume: 17 ISSN: 0975-1599 ISO Abbreviation: Middle East Afr J Ophthalmol Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-09-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101521797 Medline TA: Middle East Afr J Ophthalmol Country: India |
Other Details:
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Languages: eng Pagination: 207-9 Citation Subset: - |
Affiliation:
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Ophthalmic Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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