Document Detail

Spontaneous vertebral artery dissection as a complication of autosomal dominant polycystic kidney disease.
MedLine Citation:
PMID:  7810537     Owner:  NLM     Status:  MEDLINE    
Autosomal dominant polycystic kidney disease (ADPKD) may be associated with a variety of cardiovascular complications, including intracranial saccular aneurysms. In ADPKD, intracranial saccular aneurysms tend to rupture more frequently and earlier than the sporadic variety with a tendency to cluster in families. In contrast, dissecting intracranial aneurysms are rarely associated with either intracranial saccular aneurysms or ADPKD. We describe an ADPKD-1 patient whose course was complicated by a spontaneous dissection of a vertebral artery aneurysm. This particular patient had previously experienced three episodes of ascending aortic dissection with cystic medial necrosis. Intracranial vascular and aneurysmal dissection may occur in select ADPKD patients with familial clusters.
J Larranaga; G W Rutecki; F C Whittier
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  American journal of kidney diseases : the official journal of the National Kidney Foundation     Volume:  25     ISSN:  0272-6386     ISO Abbreviation:  Am. J. Kidney Dis.     Publication Date:  1995 Jan 
Date Detail:
Created Date:  1995-01-31     Completed Date:  1995-01-31     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8110075     Medline TA:  Am J Kidney Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  70-4     Citation Subset:  IM    
Department of Internal Medicine, Northeastern Ohio Universities College of Medicine, Affiliated Hospitals, Canton.
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MeSH Terms
Aneurysm, Dissecting / genetics*
Intracranial Aneurysm / genetics*
Polycystic Kidney, Autosomal Dominant / complications*,  genetics
Vertebral Artery*

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