Document Detail

Spontaneous thrombosis of an intracranial aneurysm during treatment with epsilon aminocaproic acid.
MedLine Citation:
PMID:  831307     Owner:  NLM     Status:  MEDLINE    
The authors report spontaneous thrombosis of a middle cerebral artery aneurysm in a patient receiving the anti-fibrinolytic agent, epsilon aminocaproic acid. Intense vasospasm and profound neurologic deficit accompanied the initial hemorrhage. Follow-up angiography two, four and ten weeks following the initial hemorrhage demonstrated occlusion of the aneurysm and progressive thrombosis of a middle cerebral artery branch despite the disappearance of vasospasm. The patient had a persistent hemiparesis.
R M Scott; E Garrido
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Surgical neurology     Volume:  7     ISSN:  0090-3019     ISO Abbreviation:  Surg Neurol     Publication Date:  1977 Jan 
Date Detail:
Created Date:  1977-02-24     Completed Date:  1977-02-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0367070     Medline TA:  Surg Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  21-3     Citation Subset:  IM    
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MeSH Terms
6-Aminocaproic Acid / adverse effects*
Aminocaproic Acids / adverse effects*
Cerebral Hemorrhage / drug therapy
Intracranial Aneurysm / complications*,  drug therapy
Intracranial Embolism and Thrombosis / chemically induced*,  physiopathology
Reg. No./Substance:
0/Aminocaproic Acids; 60-32-2/6-Aminocaproic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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