Document Detail

Spontaneous termination of atrial fibrillation: study of the effect of atrial geometry in a biophysical model.
MedLine Citation:
PMID:  19964637     Owner:  NLM     Status:  MEDLINE    
We studied the mechanisms of spontaneous termination of atrial fibrillation in a biophysical model of human atria, during the eight seconds preceding termination. The earliest detectable changes in the cycle length and the number of wavefronts occurred about three seconds prior to termination. We compared the mechanisms involved in the right and left atrium and investigated the effects of atrial geometry on the termination processes. We observed that cycle length started to increase 800 ms earlier in the left atrium than in the right atrium. Similarly, the number of wavefronts decreased even 1800 ms earlier in the left atrium than in the right one. Significantly fewer episodes terminated in the left atrium. Four areas of the atrial geometry showing distinct termination mechanisms were identified.
Laurent Uldry; Nathalie Virag; Vincent Jacquemet; Jean-Marc Vesin; Lukas Kappenberger
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2009     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2009  
Date Detail:
Created Date:  2009-12-07     Completed Date:  2010-04-08     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4504-7     Citation Subset:  IM    
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MeSH Terms
Atrial Fibrillation / physiopathology*
Heart Atria / anatomy & histology*
Magnetic Resonance Imaging
Models, Biological*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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