Document Detail

Spontaneous squamous cell carcinoma of the tongue and multiple bronchioloalveolar carcinomas in a Virginia opossum (Didelphis virginiana).
MedLine Citation:
PMID:  11945013     Owner:  NLM     Status:  MEDLINE    
Two primary tumours, squamous cell carcinoma of the tongue and multiple bronchioloalveolar carcinomas, were diagnosed in a Virginia opossum (Didelphis virginiana). Two oral masses were located in the right ventrolateral surface of the tongue, near the frenulum, and the lungs contained multiple, widely distributed, nodular masses. Microscopically, the oral masses were composed of invasive cords of pleomorphic, polyhedral cells, typical of squamous cells. The multiple pulmonary masses consisted of non-ciliated, cuboidal, columnar, or occasionally polyhedral cells arranged in an alveolar pattern with multifocal areas of necrosis. This is the first report of spontaneous oropharyngeal squamous cell carcinoma in the Virginia opossum. However, multiple pulmonary adenomas have been reported previously in this species, the lesions being similar to those in sheep pulmonary adenomatosis (jaagsiekte). In the present study, immunohistochemical examination of the pulmonary tumours with a rabbit polyclonal antiserum to jaagsiekte retroviral capsid protein proved negative.
D Y Kim; M A Mitchell; M De las Heras; H W Taylor; D-Y Cho
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of comparative pathology     Volume:  126     ISSN:  0021-9975     ISO Abbreviation:  J. Comp. Pathol.     Publication Date:    2002 Feb-Apr
Date Detail:
Created Date:  2002-04-11     Completed Date:  2002-10-18     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0102444     Medline TA:  J Comp Pathol     Country:  England    
Other Details:
Languages:  eng     Pagination:  226-30     Citation Subset:  IM    
Copyright Information:
Copyright Harcourt Publishers Ltd.
Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803, USA.
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MeSH Terms
Adenocarcinoma, Bronchiolo-Alveolar / pathology,  veterinary*
Carcinoma, Squamous Cell / pathology,  veterinary*
Fatal Outcome
Lung Neoplasms / pathology,  veterinary*
Neoplasms, Multiple Primary / pathology,  veterinary*
Pulmonary Alveoli / pathology
Tongue Neoplasms / pathology,  veterinary*

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