Document Detail

Spontaneous spinal Cerebrospinal Fluid leaks as the cause of subdural hematomas in elderly patients on anticoagulation.
MedLine Citation:
PMID:  19199465     Owner:  NLM     Status:  In-Process    
Subdural hematoma is a relatively common complication of long-term anticoagulation, particularly in the elderly. The combination of anticoagulation and cerebral cortical atrophy is believed to be sufficient to explain the subdural bleeding. The authors report a series of elderly patients who were on a regimen of anticoagulation and developed chronic subdural hematomas (SDHs) due to a spontaneous spinal CSF leak. They reviewed the medical records and imaging studies of a consecutive group of patients with spontaneous intracranial hypotension who were evaluated at Cedars-Sinai Medical Center. Among 141 patients with spontaneous spinal CSF leaks and spontaneous intracranial hypotension, 3 (2%) were taking anticoagulants at the time of onset of symptoms. The mean age of the 3 patients (1 woman and 2 men) was 74 years (range 68-86 years). All 3 patients had chronic SDHs measuring between 12 and 23 mm in maximal diameter. The SDHs resolved after treatment of the underlying spontaneous spinal CSF leak, and there was no need for hematoma evacuation. Epidural blood patches were used in 2 patients, and percutaneous placement of a fibrin sealant was used in 1 patient. The presence of an underlying spontaneous spinal CSF leak should be considered in patients with chronic SDHs, even among the elderly taking anticoagulants.
Wouter I Schievink; M Marcel Maya; Brian K Pikul; Charles Louy
Related Documents :
2775015 - Normal cerebrospinal fluid dynamics. a study with intraventricular injection of 111in-d...
20148725 - Correlation between glucose and bupivacaine levels in cerebrospinal fluid after spinal ...
12499215 - Penetration of dihydroartemisinin into cerebrospinal fluid after administration of intr...
1708265 - Efficacy of recombinant human granulocyte colony-stimulating factor on neutropenia in p...
6945105 - The treatment of obsessional neurosis in a family setting.
24318165 - The prevalence, radiographic appearance, and characteristics of zygomatic air cell defe...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  112     ISSN:  1933-0693     ISO Abbreviation:  J. Neurosurg.     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  295-9     Citation Subset:  AIM; IM    
Department of Neurosurgery, The Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Molecular screening test in familial forms of cerebral cavernous malformation: the impact of the Mul...
Next Document:  The role of adenosine in hypercarbic hyperemia: in vivo and in vitro studies in adenosine 2(A) recep...