Document Detail

Spontaneous severe ovarian hyperstimulation syndrome in successive pregnancies with successful outcomes.
MedLine Citation:
PMID:  19155932     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Ovarian hyperstimulation syndrome is a known complication of ovarian stimulation, particularly with injectable gonadotropins. Spontaneous ovarian hyperstimulation is rare and often involves a conformational change in the follicle-stimulating hormone receptor, increasing its binding with human chorionic gonadotropin or thyroid-stimulating hormone. Few data are available regarding the management or outcomes of spontaneous ovarian hyperstimulation syndrome. CASE: A 23-year-old white female without history of infertility treatment presented with ovarian hyperstimulation syndrome in two pregnancies. The patient was treated by paracentesis catheter placement and albumin replacement. She had regression of symptoms between 11 weeks and 12 weeks of gestation in both pregnancies and delivered healthy term infants. CONCLUSION: The case presented involves a patient with spontaneous severe ovarian hyperstimulation syndrome in two successive pregnancies. The patient was managed aggressively with paracentesis and albumin replacement resulting in two successful pregnancies.
Todd R Lovgren; Paul G Tomich; Carl V Smith; Teresa G Berg; Victoria Maclin
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  113     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-01-21     Completed Date:  2009-02-23     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  493-5     Citation Subset:  AIM; IM    
Division of Maternal Fetal Medicine, Nebraska Medical Center, Omaha, Nebraska, USA.
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MeSH Terms
Ascites / etiology*,  therapy
Colloids / therapeutic use
Fluid Therapy
Ovarian Hyperstimulation Syndrome / complications*,  therapy*
Serum Albumin / therapeutic use
Young Adult
Reg. No./Substance:
0/Colloids; 0/Serum Albumin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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