Document Detail

Spontaneous rupture of subserous uterine veins during late pregnancy after in vitro fertilization.
MedLine Citation:
PMID:  19463999     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To report the clinical presentation and treatment of spontaneous rupture of uterine surface veins during late pregnancy after in vitro fertilization (IVF). DESIGN: Case report. SETTING: Medical Unit of Third Hospital of Peking University, Beijing, China. PATIENT(S): A total of 573 pregnancies resulting from IVF in our hospital were reviewed for examples of spontaneous rupture of uterine veins. INTERVENTION(S): Data were obtained from medical charts, delivery summaries, and surgical reports in the historical files. MAIN OUTCOME MEASURE(S): Explorative laparotomy was performed. RESULT(S): Three women were found experiencing significant intra-abdominal bleeding in the third trimester of pregnancy due to a lesion resulting from endometriosis and chronic pelvic inflammatory disease. The intra-abdominal bleeding occurred between 29 and 35 weeks of gestation. A major prenatal symptom was severe abdominal pain in all of the cases. The pain was not relieved by the application of tocolytics or mild analgesics. Explorative laparotomy, performed in all three cases, revealed the presence of massive intra-abdominal bleeding stemming from subserous uterine veins. Fetal death occurred in one case. Immediate institution of effective resuscitative measures and early surgical intervention were essential to both fetal and maternal survival. CONCLUSION(S): Patients undergoing IVF treatment may be at increasing risk for intra-abdominal bleeding in the third trimester of pregnancy.
Yan Zhang; Yangyu Zhao; Yuan Wei; Rong Li; Jie Qiao
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-05-21
Journal Detail:
Title:  Fertility and sterility     Volume:  92     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-29     Completed Date:  2009-07-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  395.e13-6     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Third Hospital of Peking University, Beijing, People's Republic of China.
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MeSH Terms
Apgar Score
Blood Loss, Surgical
Blood Transfusion
Cesarean Section
Fertilization in Vitro / adverse effects*
Infant, Newborn
Pregnancy Complications / diagnosis*,  surgery
Pregnancy Trimester, Third
Rupture, Spontaneous / diagnosis*,  surgery
Treatment Outcome
Uterus / blood supply*

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