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Spontaneous rupture of hepatic artery aneurysm associated with polyarteritis nodosa.
MedLine Citation:
PMID:  21265359     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Polyarteritis nodosa (PAN) is a vasculitis, which often involves small and medium sized visceral arteries. This condition may result in multifocal aneurismal formation and end-organ damage. Uncommonly, PAN may present with rupture of hepatic artery aneurysms. Here, we report a rare case of a ruptured intrahepatic aneurysm associated with PAN. A 79-year-old woman presenting with abdominal pain had CT scan of the abdomen, which revealed hematoma in the right hepatic lobe. Visceral angiogram confirmed pseudo-aneurysm of a right hepatic arterial branch, and this was managed with endovascular coil embolization. The diagnosis of PAN was made and corticosteroid therapy was initiated. We also performed a literature review to define this condition's demographics, clinical presentations, and appropriate management. The review revealed 17 published cases of ruptured PAN-related intrahepatic aneurysms. We conclude that unexplained findings of visceral arterial aneurysms should prompt investigations for vasculitis as the etiology.
Authors:
Brodie A Parent; Sung W Cho; David G Buck; Michael A Nalesnik; T Clark Gamblin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American surgeon     Volume:  76     ISSN:  0003-1348     ISO Abbreviation:  Am Surg     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2011-01-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370522     Medline TA:  Am Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1416-9     Citation Subset:  IM    
Affiliation:
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
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